Research Publications
1
Rose R, Karthikeyan M, Anandan B, Jayaraman G. Myocilin mutation among primary open angle glaucoma patients of kanyakumari district, South India.  Molecular Vision, 2007 Apr 2; 13:497-503. PMID: 17417611 (IF (2006): 2.38).
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Karthikeyan M, Rose R, Shridevi V, Anandan B, Shanmugasundaram S, Mohan D,  Ramesh A, Jayaraman G. Core Promoter Variants (A-20C, T-18C and G-6A) of the Angiotensinogen (AGT) Gene are not Significantly Associated with Hypertension in Patients of Tamilnadu, India. International Journal of Human Genetics, 2009 Mar; 9(1):  13-19.
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Singh KhD, Karthikeyan M*, Kirubakaran P, Nagamani S. Pharmacophore filtering and 3D-QSAR in the discovery of new JAK2 inhibitors. Journal of Molecular Graphics and Modelling, 2011 Sep; 30:186-97. PMID: 21831680, DOI: 10.1016/j.jmgm.2011.07.004 (IF (2010) : 2.033).
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Singh KhD, Karthikeyan M*. Molecular Modeling, Quantum Polarized Ligand Docking and Structure Based 3D-QSAR study of imidazole series as Dual Endothelin and Angiotensin II Receptor Antagonists. Acta Pharmacologica Sinica (NPG), 2013 Dec 1; 34, 1592-1606. PMID: 24304920, DOI: 10.1038/aps.2013.129  (IF (2012): 2.496)
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Singh KhD, Ajay J, Harpreet K, Ritushree K, Karthikeyan M*. Gender specific association of RAS gene polymorphism with essential hypertension – a case control study.  BioMed Research International, 2014 Apr 17; PMID: 24860821, (DOI: 10.1155/2014/538053).  (IF (2013): 2.706)
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Singh KhD, Naveena Q, Karthikeyan M*. Jak2 inhibitor – a jackpot for pharmaceutical industries: a comprehensive computational method in the discovery of new potent Jak2 inhibitors. Molecular BioSystems (RSC), 2014 Apr 14; 10. 2146-2159. PMID: 24874539, DOI: 10.1039/c4mb00071d  (IF(2013): 3.35)
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Singh KhD, Karthikeyan M*. Combined sequence and sequence-structure-based methods for analyzing RAAS gene SNPs: a computational approach. Journal of Receptors and Signal Transduction Research, 2014 Dec 01; 34(6): 513-526. PMID: 24878201, DOI: 10.3109/10799893.2014.922575 (IF (2013):1.611)
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Singh KhD, Ajay J, Kaur H, Kukreti R, Karthikeyan M*. Renin Angiotensin System gene polymorphisms in response to antihypertensive drugs and visit-to-visit blood pressure variability in essential hypertensive patients. Current Pharmacogenomics and Personalized Medicine, 2014; 12 (1), 227-235 (Bentham Science Publishers). DOI: 10.2174/1875692113666150420225829.
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Lakshmanan Loganathan and Karthikeyan Muthusamy*. Investigation of drug interaction potentials and binding modes on direct renin inhibitors. A computational modeling study. Letters in Drug Design and Discovery, 2019, 16(8); 919-938. DOI: 10.2174/1570180815666180827113622. (IF: 0.924)
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Lakshmanan Loganathan, Krishnasamy Gopinath, Vadivel Murugan Sankaranarayanan, Ritushree Kukreti, Kannan Rajendran, Jung-Kul Lee, and Karthikeyan Muthusamy. Computational and Pharmacogenomic Insights on Hypertension Treatment: Rational Drug Design and Optimization Strategies. Current Drug Targets. 2020; 21(1):18-33. doi: 10.2174/1389450120666190808101356 (IF: 3.10)
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Lakshmanan LoganathanBeena Briget KuriakoseSakeena Mushfiq, Karthikeyan Muthusamy*. Mechanistic insights on nsSNPs on binding site of renin and cytochrome P450 proteins: A computational perceptual study for pharmacogenomics evaluation. Journal of Cellular Biochemistry, June 2021, Doi: 10.1002/jcb.30069. (IF: 4.429)
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Nagamani S, Shanmuga Perumal M, Leela Shanmuga Perumal R, Kesavan C, Karthikeyan M*. ACE DD genotype associated with the female Chronic Kidney Disease patients of Tamilnadu population. The Egyptian Journal of Medical Human Genetics, 2015 Jan 01, 16 (1): 29-33. (Elsevier publication)
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Singh KhD, Ajay J, Kaur H, Kukreti R, Karthikeyan M*. Renin Angiotensin System gene polymorphisms in response to antihypertensive drugs and visit-to-visit blood pressure variability in essential hypertensive patients. Current Pharmacogenomics and Personalized Medicine, 2014 12 (1), 227-235 (Bentham Science Publishers)
15
Singh KhD, Karthikeyan M*. Combined sequence and sequence-structure-based methods for analyzing RAAS gene SNPs: a computational approach. Journal of Receptors and Signal Transduction Research, 2014 Dec 01; 34 (6):  513-526. (IF (2013):1.611)
16
Singh KhD, Naveena Q, Karthikeyan M*. Jak2 inhibitor – a jackpot for pharmaceutical industries: a comprehensive computational method in the discovery of new potent Jak2 inhibitors. Molecular BioSystems (RSC), 2014 Apr 14; 10. 2146-2159. (IF(2013): 3.35)
17
Singh KhD, Ajay J, Harpreet K, Ritushree K, Karthikeyan M*. Gender specific association of RAS gene polymorphism with essential hypertension – a case control study.  BioMed Research International, 2014 Apr 17; (DOI: 10.1155/2014/538053). (IF (2013): 2.706)
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Karthikeyan M*, Shridevi V, Rajiv Rose, Anandan B, Singh KhD, Shanmugasundaram S,  Mohan D, Ramesh, Jayaraman G. Angiotensin Gene Polymorphisms (T174M and M235T) are Significantly Associated with the Hypertensive Patients of Tamil Nadu, South India. International Journal of Human Genetics, 2013 Dec 1; 13(4): 201-207. (IF (2012): 0.19)
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Singh KhD, Karthikeyan M*. Molecular Modeling, Quantum Polarized Ligand Docking and Structure Based 3D-QSAR study of imidazole series as Dual Endothelin and Angiotensin II Receptor Antagonists. Acta Pharmacologica Sinica (NPG), 2013 Dec 1; 34, 1592-1606. (IF (2012): 2.496)
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Devi Kasinathan, , Nisha RG, Prabhu NM, Manikandan R, Karthikeyan M. Awareness on Type II Diabetes and Its Complication among Sivaganga District Population in Tamilnadu: A Cross Section Survey. Journal of Advanced Scientific Research, 2013 Feb 1. 4(1): 38-42.